Introduction: Bio-nanotechnology is an area of great research interest. Fundamental to research in this area is the technique of single molecule detection � the ultimate limit in nanotechnology. In contrast to conventional technology, the art of observing single molecules requires new techniques in order to limit the generation and collection of background noise while maximizing the collection of signal. Only in 1993 were single dye molecules were observed at room temperature [1] utilizing near-field optics and only in 1996 were single molecules observed using far-field techniques[2]. In the past, we combined a discarded AFM stage and a conventional microscope to build a cost effective confocal microscope. Unfortunately, the environment greatly affects lifetime.
Short term objectives: We propose to develop and apply a novel confocal microscope that overcomes three key problems associated with current practices.
Long term objectives: Utilization of this microscope:
Research Plan: (Click on the diagram)
Next steps (available Master's Projects):
© Jonathon David White - "With a Servant's Heart" - Last updated: |